The C terminus of DJ-1 determines its homodimerization,MGO detoxification activity and suppression of ferroptosis

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作者 Li Jiang ^[1] Xiao-bing Chen ^[1] Qian Wu ^[1] Hai-ying Zhu ^[1] Cheng-yong Du ^[2] Mei-dan Ying ^[1] Qiao-jun He ^[3] Hong Zhu ^[1] Bo Yang ^[1] Ji Cao ^[3] 学术成果认领

作者单位 Institute of Pharmacology and Toxicology,Zhejiang Province Key Laboratory of Anti-Cancer Drug Research,College of Pharmaceutical Sciences,Zhejiang University,Hangzhou 310058,China ^[1] Department of Breast Surgery,The First Affiliated Hospital,College of Medicine,Zhejiang University,Hangzhou 310006,China ^[2] Institute of Pharmacology and Toxicology,Zhejiang Province Key Laboratory of Anti-Cancer Drug Research,College of Pharmaceutical Sciences,Zhejiang University,Hangzhou 310058,China;Innovation Institute for Artificial Intelligence in Medicine,Zhejiang University,Hangzhou 310058,China;Cancer center of Zhejiang University,Hangzhou 310058,China ^[3]

关键词 DJ-1 C terminus homodimerization methylglyoxal(MGO)detoxification deglycation ferroptosis HEK293T cells DJ-1-/-mouse embryonic fibroblast cells

栏目名称 Anti-tumor Pharmacology

发布时间 2021-07-22

基金项目

This work was supported by grants from National Science&Technology Major Project"Key New Drug Creation and Manufacturing Program" China the National Natural Science Foundation of China and Zhejiang Medical and Health Science and Technology Program

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中国药理学报（英文版）

2021年42卷7期

1150-1159页

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The C terminus of DJ-1 determines its homodimerization,MGO detoxification activity and suppression of ferroptosis

中国药理学报（英文版）

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中国药理学报（英文版）

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The C terminus of DJ-1 determines its homodimerization,MGO detoxification activity and suppression of ferroptosis

中国药理学报（英文版）

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中国药理学报（英文版）

相关期刊

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