摘要目的 探讨缺血修饰白蛋白(IMA)对急性冠脉综合征(ACS)患者PCI术后的临床价值的预测.方法 收集攀钢总医院心内科2010年1月至2012年7月ACS经PCI术后的患者109例.患者发病后6h之内测定IMA,经PCI及术后标准化治疗,随访6个月根据心血管事件是否发生,分为事件组和无事件组.结果 有效随访患者101例,其中事件组26例(25.74％),无事件组75例(74.26％).左室射血分数比较,事件组[(45±7)％]低于无事件组[(52±10)％],差异有统计学意义(t=1.894,P＜0.05).血清IMA比较,事件组[(105.51±13.26) U/ml]明显高于无事件组[(85.18±11.36) U/ml],差异有统计学意义(t=7.3518,P＜0.01).校正其它心血管危险因素后,IMA仍然是心血管事件的独立危险因素(OR =1.76,95％ CI:1.3 ～2.23,P=0.01).结论 IMA对ACS患者PCI术后6个月内心血管事件有很好的临床预测价值.

abstractsObjective Exploring clinical prediction value of the ischemia modified albumin (IMA) for acute coronary syndrome (ACS) patients after the percutaneous coronary intervention (PCI).Methods A total of 109 cases of the PCI postoperative patients of ACS at the Panggang General Hospital from January 2010 to July 2012 were included.IMA was determined within 6 hours after admission,and standardized treatment after PCI.After a 6-month follow-up,they were divided into the event group and non-event group according to cardiovascular events occurrence.Results 101 cases were followed-up,including 26 cases of cardiovascular events (25.74％) and 75 cases of no cardiovascular events (74.26％).The left ventricular ejection fraction of the event group [(45 ± 7)％] was significantly lower than the non-event group [(52 ± 10) ％] (t =1.894,P ＜ 0.05).Serum IMA of the event group[(105.51 ± 13.26) U/ml]was significantly higher than the non-event group [(85.18 ± 11.36) U/ml] (t =7.3518,P ＜0.01).After controlling other cardiovascular risk factors,IMA was still independent risk factors for cardiovascular events (OR =1.69,95％ CI: 1.18 ～ 2.13,P =0.01).Conclusions IMA have very good clinical prediction value of cardiovascular events occurrence for ACS after PCI.