三种超声途径测宫颈长度预测早产的对比分析
Comparative analysis of three ultrasonic methods for the cervical length in predicting the preterm birth
摘要目的:探讨超声测宫颈长度预测早产的临床意义,并对经腹、经阴道与经会阴三种超声途径测宫颈长度预测早产进行比较。方法对2012年1月至2013年12月有先兆早产征象来本院就诊的孕妇(840例)行超声测宫颈长度预测早产,按不同测量宫颈长度途径分为3组,每组280例,经腹测量宫颈长度(Ⅰ组)、经阴道测量宫颈长度(Ⅱ组)、经会阴测量宫颈长度(Ⅲ组),记录宫颈长度( CL ),追踪妊娠结局,并对三种测量方法进行比较。结果Ⅰ组孕妇接受率为100%(280/280),宫颈实现率为85.0%(238/280),CL<3 cm组早产率为48.6%(18/37),CL≥3 cm组早产率为17.9%(36/201),CL<3 cm预测早产敏感性为33.3%(18/54);Ⅱ组孕妇接受率为81.8%(229/280),宫颈实现率为98.7%(226/229),CL<3 cm组早产率为37.8%(28/74),CL≥3 cm组早产率为13.2%(20/152),CL<3 cm预测早产敏感性为58.3%(28/48);Ⅲ组孕妇接受率为99.3%(278/280),宫颈实现率为98.2%(273/278),CL<3 cm组早产率为37.1%(33/89),CL≥3 cm组早产率为13.6%(25/184),CL<3 cm预测早产敏感性为56.9%(33/58)。三组CL<3 cm组早产率(48.6%,37.8%,37.1%)均明显高于CL≥3 cm组早产率(17.9%,13.2%,13.6%),差异有统计学意义( P <0.05)。Ⅱ组孕妇接受率(81.8%)明显低于Ⅰ组(100%)和Ⅲ组(99.3%),差异有统计学意义( P <0.05)。Ⅰ组宫颈实现率85%明显低于Ⅱ组98.7%和Ⅲ组98.2%,差异有统计学意义( P <0.05);Ⅰ组CL<3 cm预测早产敏感性33.3%,明显低于Ⅱ组(58.3%)和Ⅲ组(56.9%),差异有统计学意义( P <0.05)。结论超声测宫颈长度预测早产有较大临床意义,相比之下经会阴途径更具优势,值得推广。
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abstractsObjective To compare three ultrasonic methods of transabdominal , transvaginal , and transperineal ultrasonogra-phy for the cervical length ( CL) in predicting the preterm birth .Methods The pregnancy women with threatened preterm labor in Hunan Provincial Hospital of Maternal and Child Health from January , 2012 to December, 2013 were chosen to measure the cervical length by sonography , and were randomly divided into three guoups ( 280 pregnancy women in each group ) , including Group Ⅰ( transabdominal ) , groupⅡ( transvaginal ) , and group Ⅲ ( transperineal ) .The cervical length and the pregnancy outcome were fol-lowed up.Results The acceptance rate of group Ⅱ(81.8%=229/280) was significantly lower than that of groupⅠ(100%=280/280)and group Ⅲ(99.3%=278/280)( P <0.05).The realization ratio of the cervix in group Ⅰ(85.0%=238/280) was signifi-cantly lower than that of group Ⅱ(98.7%=226/229) and group Ⅲ (98.2%=273/278) ( P <0.05).The preterm birth rate of 48.6%(18/37) in groupⅠ, 37.8%(28/74) in groupⅡ, and 37.1%(33/89) in groupⅢin the pregnancy women with CL <3 cm was significantly higher than the corresponding preterm birth rate of 17.9%(36/201) in groupⅠ, 13.2%(20/152)in groupⅡ, and 13.6% (25/184) in groupⅢin the pregnancy women with CL≥3 cm.The sensitivity of groupⅠ(33.3%=18/54) was significantly lower than that of group Ⅱ(58.3%=28/48) and group Ⅲ(56.9%=33/58).Conclusions The cervical length measured by ultra-sound is valuable in predicting preterm birth among the pregnancy women with threatened preterm birth .The transperineal ultrasonogra-phy is superior to transabdominal and transvaginal ultrasonography in predicting preterm birth , and is worth being popularized .
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