摘要心力衰竭作为各种心脏疾病的终末阶段,是当今严重威胁公众健康的心血管疾病之一,住院率位居各种心血管疾病前列.近年来关于心力衰竭标记物在心力衰竭诊断、治疗及预后评估等方面的研究取得了很大进展,如B型脑钠肽(BNP)可部分反映心脏血流动力学的改变,肌钙蛋白能提示心肌梗死或损伤,可溶性ST2 (sST2)和半乳糖凝集素3(Gal-3)表明心肌的重塑和纤维化,C反应蛋白(CRP)、胱抑素C(CysC)、降钙素(PCT)及和肽素对病情的严重程度和预后都有较高参考价值,微小RNA(miRNA)从基因调控方面参与心力衰竭进程等.

abstractsHeart failure is a serious and terminal stage of various cardiovascular diseases,is one of the most important heart diseases,and it also the most common reason for hospitalization.In recent years,studies on new markers in the diagnosis,treatment and prognosis of heart failure have made great progress,such as B-type brain natriuretic peptide can partially reflect hemodynamic imbalance,troponin can indicate cardiomyocyte injury,soluble ST2 and galectin-3 indicate myocardium remodeling and fibrosis,C-reactive protein,cystatin C and procalcitonin,and copeptin have significant prognostic value for outcomes,microRNA in the regulation of gene expression influence heart failure.