摘要目的:对比右半结肠癌并发不全性肠梗阻患者实施腹腔镜下完整结肠系膜切除术(complete mesocolic excision，CME)应用中间尾侧联合入路与头侧中间入路的效果。方法:回顾性分析2014年1月至2019年1月大连市第三人民医院收治右半结肠癌并发不全性肠梗阻90例患者的临床资料。均接受腹腔镜下右半结肠切除术、CME加D3淋巴结清扫。按选择不同手术入路进行分组，其中44例患者采用中间尾侧联合入路 (观察组)，另46例患者采用头侧中间入路(对照组)。对两组的术中、术后及并发症情况进行统计学比较。结果:与对照组比较，观察组的术中出血量明显减少[(105.3±22.6) ml与(309.6±28.0) ml， t＝13.698]、手术时间明显缩短[(165.2±17.9) min与(219.5±21.5) min， t＝8.327]，差异均有统计学意义( P均<0.05)。而观察组与对照组在清扫淋巴结数量[(21.4±7.8)枚与(20.4±6.6)枚， t＝0.534]、清扫淋巴结≥12枚比例[86.4%(38/44)与84.8%(39/46)，χ 2＝0.208]、术后并发症[6.8%(3/44)与10.9%(5/46)，χ 2＝0.318]、术后住院时间[(11.8±1.6) d与(12.5±2.3) d， t＝0.986]等指标的比较差异均无统计学意义( P均>0.05)。 结论:右半结肠癌并发不全性肠梗阻实施腹腔镜下CME时采用中间尾侧联合入路安全可行，与头侧中间入路相比可减少术中出血量并使手术时间明显缩短。

abstractsObjective:To compare the effect of midcaudal combined approach and the cephalic middle approach in laparoscopic complete mesocolic excision (CME) in the treatment of right colon cancer complicated with incomplete intestinal obstruction.Methods:From January 2014 to January 2019, 90 patients with right colon cancer complicated with incomplete intestinal obstruction admitted to the Third People′s Hospital of Dalian were retrospectively analyzed.All patients underwent laparoscopic right hemicolectomy, CME plus D3 lymph node dissection.According to the choice of different surgical approaches, 44 patients were treated with the midcaudal combined approach (observation group) and the other 46 patients were treated with cephalic middle approach (control group). The intraoperative, postoperative and complications of the two groups were compared statistically.Results:Compared with the control group, the bleeding volume in the observation group was significantly reduced ((105.3±22.6) ml vs.(309.6±28.0) ml, t=13.698), the operation time was significantly shortened ((165.2±17.9) min vs.(219.5±21.5) min, t=8.327), and the differences were statistically significant (all P<0.05). There were no significant differences in the number of lymph nodes dissected ((21.4±7.8)vs.(20.4±6.6), t=0.534), the proportion of lymph nodes dissected≥12(86.4%(38/44)vs.84.8%(39/46), χ 2=0.208), the complications after operation(6.8%(3/44)vs.10.9%(5/46), χ 2=0.318), the length of hospital stay after operation ((11.8±1.6) d vs.(12.5±2.3) d, t=0.986), the difference was statistically significant (all P>0.05). Conclusion:It is safe and feasible to use the middle caudal approach in laparoscopic CME for right colon cancer complicated with incomplete ileus. Compared with the cephalic middle approach, it can reduce thebleeding volume and shorten the operation time.