首页 > 癌症生物学与医学（英文版） > Identification of immune reconstitution and hematopoiesis restoration by scRNA-seq in bone marrow of multiple myeloma patients treated with high-dose melphalan following auto-HSCT

Identification of immune reconstitution and hematopoiesis restoration by scRNA-seq in bone marrow of multiple myeloma patients treated with high-dose melphalan following auto-HSCT

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摘要Multiple myeloma(MM)is a clonal plasma cell malignancy that arises within the bone marrow(BM),leading to disrup-tions in normal hematopoiesis,immune dysfunction,oste-olytic bone lesions,anemia,and renal impairment1.

作者 Qian Li ^[1] Yaling Wang ^[2] Hongfeng Yuan ^[2] Qiaomei Cai ^[2] Lina Zhao ^[3] Li Lin ^[4] Shuang Gao ^[4] Lin Chen ^[4] Zhiying Zhang ^[4] Jing Ma ^[4] Su Liu ^[4] Zeng Cao ^[5] Haifeng Zhao ^[5] Yufei Wang ^[2] Shihui Li ^[2] Pan Lv ^[2] Huihui Zhang ^[2] Guowen Wang ^[6] Guang Yang ^[2] Xiaodong Zhang ^[2] Yafei Wang ^[1] 学术成果认领

作者单位 Department of Hematology,Tianjin Medical University Cancer Institute and Hospital,National Clinical Research Center of Cancer,Tianjin Key Laboratory of Cancer Prevention and Therapy,Tianjin's Clinical Research Center for Cancer,Tianjin 300060,China;Department of Blood and Marrow Transplantation,Tianjin Cancer Hospital Airport Hospital,Tianjin 300308,China ^[1] State Key Laboratory of Druggability Evaluation and Systematic Translational Medicine,Tianjin Key Laboratory of Digestive Cancer,Department of Gastrointestinal Cancer Biology,Tianjin Cancer Institute,Liver Cancer Center,Tianjin Medical University Cancer Institute and Hospital,National Clinical Research Center for Cancer,Tianjin's Clinical Research Center for Cancer,Tianjin 300060,China ^[2] Department of Blood and Marrow Transplantation,Tianjin Cancer Hospital Airport Hospital,Tianjin 300308,China;State Key Laboratory of Druggability Evaluation and Systematic Translational Medicine,Tianjin Key Laboratory of Digestive Cancer,Department of Gastrointestinal Cancer Biology,Tianjin Cancer Institute,Liver Cancer Center,Tianjin Medical University Cancer Institute and Hospital,National Clinical Research Center for Cancer,Tianjin's Clinical Research Center for Cancer,Tianjin 300060,China ^[3] Department of Blood and Marrow Transplantation,Tianjin Cancer Hospital Airport Hospital,Tianjin 300308,China ^[4] Department of Hematology,Tianjin Medical University Cancer Institute and Hospital,National Clinical Research Center of Cancer,Tianjin Key Laboratory of Cancer Prevention and Therapy,Tianjin's Clinical Research Center for Cancer,Tianjin 300060,China ^[5] National Key Laboratory of Druggability Evaluation and Systematic Translational Medicine,Tianjin's Clinical Research Center for Cancer,Department of Bone and Soft Tissue Tumors,Tianjin Medical University Cancer Institute and Hospital,National Clinical Research Center for Cancer,Tianjin 300060,China ^[6]

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DOI 10.20892/j.issn.2095-3941.2025.0585

发布时间 2026-04-15（万方平台首次上网日期，不代表论文的发表时间）

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