摘要Mucormycosis,a rapidly invasive form of fungal infection caused by Mucorales fungi,has high morbidity and mortality rates.Rhino-orbital-cerebral mucormycosis is the most common form of mucormycosis.With the coronavirus disease 2019(COVID-19)outbreak,a causal correlation between mucormycosis and COVID-19 has been suspected,contributing to the abrupt increase in opportunistic fungal infection cases.We present a case of a Southeast Asian woman in her 60s with complaints of pus discharge in the palatal region with maxillary teeth mobility for 3 months.Physical examination revealed multiple nonvital upper teeth with severe mobility.Inci-sional biopsy of the maxilla and multidetector computed tomography of the head and neck confirmed the diagnosis of osteomyelitis of the maxilla secondary to mucormycosis.Surgical treatment was performed,and amphotericin B and posaconazole were administered.No operative complications or further bone destruction were observed at 8 months postoperatively.