Effects of cordyceps sinensis on murine T lymphocyte subsets

二维码有效期 120s

摘要It was shown by flow cytometry analysis that crystalized preparation of Cordyceps sinensis (Cs-Cr) caused significant elevation of the number of T helper cells and Lyt-1/Lyt-2 (T helper to T suppressor cell) ratio both in peripheral blood and the treated mice spleen. The spleen weight, phagocyte counts and phagocytic activity were also elevated in the treated group. In addition, Cs-Cr could protect T helper cells from the immunosuppressive effects of prednisolone acetate and cyclophosphamide. These results further substantiate the fact that Cs-Cr is an immunoregulator/biological response modifier of cellular immunity and may be potentially useful in handling immunodeficient or immunosuppressed patients.

作者 Chen Guo-zhen ^[1] Chen Guo-lin ^[1] Sun Tsieh ^[2] Gerry C. Hsieh ^[2] Joan M. Henshall ^[2] 学术成果认领

作者单位 Institute of Combined Western and Traditional Chinese Medicine, Hunan Medical University, Changsha 410078 ^[1] The Clinical Laboratory of North Shore Hospital, Cornell University, NY, USA ^[2]

主题词冬虫夏草属(Cordyceps)T淋巴细胞亚群(T-Lymphocyte Subsets)T淋巴细胞, 辅助诱导(T-Lymphocytes, Helper-Inducer)脾(Spleen)流式细胞术(Flow Cytometry)

栏目名称 Original Article

发布时间 2020-04-28