Is cerebral cavernous malformation a pre-glioma lesion?

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摘要Glioma is the most malignant tumor in the brain,the origin of glioma is still unknown.Recently some papers indicated that glioma may be developed from cerebral cavernous malformation (CCM).We describe a man with a right temporal lobe CCM,after gamma-knife radiotherapy,the patient developed a low-grade astrocytoma in the area of the preexistent CCM.This case,together with other reports,may indicated an oncogenetic properties of CCM,and we proposed that CCM may be a pre-glioma lesion.

作者单位 Department of Neurosurgery, First Affiliated Hospital of China Medical University, Shenyang, Liaoning 110001, China ;Department of Neurosurgery, 463 Hospital, Shenyang, Liaoning 110042, China ^[1] Department of Neurosurgery, First Affiliated Hospital of China Medical University, Shenyang, Liaoning 110001, China ^[2]

关键词 glioma cerebral cavernous malformation radiotherapy

栏目名称 VIEWPOINT

DOI 10.3760/cma.j.issn.0366-6999.2012.24.033

发布时间 2013-02-22

基金项目

grants from National Natural Science Foundation of China National "863" Key Project

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