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Bioresorbable scaffolds for coronary artery disease: current status and future prospective

摘要Objective To update the current status of bioresorbable scaffold,highlights the potential future prospective of innovative bioresorbable scaffold technology.Data sources Data were obtained from papers published in PubMed,presentations from the following conferences:EuroPCR,Transcatheter Cardiovascular Therapeutics,and Chinese Interventional Therapeutics.Results Bioresorbable scaffold has been introduced as a potential workhorse device for the treatment of coronary artery disease,with providing temporary vessel scaffold,then gradually being resorbed free of any caging,eventually restoring the vessel wall physiology and vasomotion.The clinical outcomes regarding the safety and efficacy following bioresorbable scaffolds implantation appear promising in the treatment of patients with either de novo lesions or acute myocardial infarction (AMI).In addition,two bioresorbable scaffolds currently investigated in Chinese population as well as several other bioresorbable scaffolds from Chinese manufactories are under development and preclinical evaluations.Conclusions Bioresorbable scaffolds with potential unique advantages have been rapidly developed and the initial clinical results are promising.Further preclinical and clinical evaluations are necessary to investigate their safety and efficacy in the treatment of Chinese patients with coronary artery disease.

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作者单位 Thorax Center, Erasmus Medical Center, Rotterdam, 3015CE, The Netherlands;Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu 210006, China [1] Department of Cardiology, Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China [2] Thorax Center, Erasmus Medical Center, Rotterdam, 3015CE, The Netherlands [3]
栏目名称 REVIEW ARTICLES
DOI 10.3760/cma.j.issn.0366-6999.20140015
发布时间 2014-03-31
基金项目
Zhang Yaojun is supported by the Jiangsu Provincial Special Program of Medical Science
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中华医学杂志(英文版)

中华医学杂志(英文版)

2014年127卷6期

1141-1148页

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