摘要Fahr's disease, or idiopathic basal ganglia calcification (IBGC), is a rare neurological syndrome characterized by abnormal calcified deposits located mostly in bilateral basal ganglia and dentate nucleus, and also in cerebral cortex, thalamus, hippocampus, cerebellar, and subcortical white matter.Clinically, it presents various symptoms, including parkinsonism (presented in 57% of the patients), chorea (19%), tremors (8%), dystonia (8%), athetosis (5%), and orofacial dyskinesia (3%).[1]
作者单位Department of Neurology, Guangdong Neuroscience Institute, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong 510080, China[1]
grants from National Key Clinical Specialist Construction Programs of China, National Natural Science Foundation of ChinaScience and Technology Planning Project of Guangdong Province,ChinaNatural Science Foundation of Guangdong Province, ChinaScience and Technology Program of Guangzhou,China