Monoclonal B-cell Lymphocytosis in a Patient with Wegener Granulomatosis: A Case Report and Update on 2016 World Health Organization Classification

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摘要The association between autoimmune disease and risk of monoclonal malignancy is well studied.However,monoclonal B-cell lymphocytosis (MBL) in patients with autoimmune diseases has rarely been reported.The newly published 2016 revision of the World Health Organization (WHO) classification of lymphoid neoplasms has officially accepted MBL as an independent disease entity.11] Herein,we present a case ofWegener granulomatosis (WG) with MBL.Through this case,the diagnosis and management of MBL as a less known condition to rheumatologists,especially under the background of an autoimmune disorder,is reviewed.Moreover,the association between autoimmune disease and risk of monoclonal malignancy is discussed.

作者单位 Department of Hematology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China ^[1] Department of Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China ^[2]

关键词 Autoimmune Diseases Lymphoma Monoclonal B-cell Lymphocytosis,Wegener Granulomatosis World Health Organization

栏目名称 Clinical Practice

DOI 10.4103/0366-6999.189926

发布时间 2016-10-24

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