摘要目的　筛选出最佳氯化钠溶液浓度、最佳滴注速度和最佳剂量；了解高渗氯化钠溶液复苏后血浆渗透压及电解质的变化情况。　方法　45只犬，制成失血性休克模型，用不同浓度和剂量的氯化钠溶液在不同滴注速度下，对失血性休克犬进行复苏，比较其复苏效果。　结果　质量浓度为75 g/L的高渗氯化钠溶液为最佳浓度，20　ml/min为最佳滴速，相当于放血量的15%（5.71　mg/kg体重）为最佳剂量；复苏效果确切，使平均动脉压恢复到基础水平的89%，且维持时间至少1 h左右。　结论　以20 ml/min的滴速，用相当于失血量15%的75 g/L氯化钠溶液复苏失血性休克效果最佳。

abstractsbjective　To find out the optimal concentration, infusion rate and dosage of sodium chloride solution for resuscitation. 　Methods　A total of 45 hemorrhagic shock dog models were established, resuscitated with sodium chloride solution with different concentration and dosage under different infusion rate and compared with the resuscitation results. 　Results　The best concentration is 75 g/L, the best infusion rate 20 ml/min, and a volume equivalent to 15% of shed blood (5.71 mg/kg) the best dosage. Such method was effective because resuscitation for MAP could be elevated to 89% of the baseline and kept stable for more than 1 hour. 　Conclusions　A volume of 75 g/L sodium chloride solution at infusion rate of 20 ml/min equivalent to 15% of shed blood can achieve the best resuscitation.