摘要目的 评估连枷胸合并严重多发伤时应用损伤控制外科(damage control surgery,DCS)原则的治疗效果. 方法 选择2002年1月-2011年12月胸壁固定合并严重多发伤连枷胸患者187例,按治疗方法不同分为三组:DCS组66例(初期肋骨悬吊牵引,延期内固定)；对照A组70例(单纯肋骨悬吊牵引)；对照B组51例(初期肋骨内固定).对各组治疗前后主要参数、病死率和并发症进行比较分析. 结果 全组并肺部感染32例,肺不张38例,急性肺损伤(acute lung injury,ALI)/ARDS 39例.死亡22例,其中ARDS 13例,张力性气胸2例,大咯血1例,心源性休克3例,颅脑损伤2例,肝脏损伤l例,总病死率11.8％.DCS组和对照A组治疗后氧合指数(oxygenation index,OI)均显著提高(P＜0.01),而对照B组OI改变较小.病死率、并发症、呼吸机、气管切开和纤维支气管镜治疗例数、平均ICU滞留天数和住院天数等指标,DCS组均最低,对照A组次之,对照B组最高(P＜0.01). 结论 DCS在连枷胸合并严重多发伤时应用可明显降低病死率和并发症.

abstractsObjective To investigate clinical effect of damage control surgery (DCS) in treatment of patients with flail chest combined with severe multiple injuries.Methods A total of 187 cases of flail chest combined with severe multiple injuries treated by fixation of floating chest wall were enrolled and divided into three groups on the basis of different treatments:DCS group (66 cases) underwent early suspension traction of ribs and delayed internal fixation of the ribs ; Group A (70 cases) underwent rib suspension traction alone; Group B (51 cases) underwent initial internal fixation of rib.Complications,mortality,and main parameters before and after operation in each group were analyzed and compared.Results Complications including pulmonary infection (32 cases),atelectasis (38 cases),and acute lung injury (ALI)/ARDS (39 cases) were found.Twenty-two cases died,including 13 deaths from ARDS,two from tension pneumothorax,one from massive hemoptysis,three from cardiac shock,two from craniocerebral injury,and one from liver trauma and thus the overall death rate occupied 11.8％.Oxygenation index (OI) had significant rise postoperatively both in the DCS group and Group A (P ＜ 0.01),but the change of OI was inappreciable in Group B.Mortality,complication rate,cases treated with mechanical ventilation,tracheotomy or fiberoptic bronchoscopy,and average length of ICU and hospital stay were the lowest in the DCS Group,followed by a relatively higher result in Group B and a much higher result in Group A (P ＜ 0.01).Conclusion DCS decreases mortality and complications dramatically when appolied to treat flail chest combined with severe multiple trauma.