摘要颅内感染是神经重症患者较常见也较严重的并发症,病死率高,对患者预后会产生极为不利的影响.对颅内感染的治疗,抗生素选择仍然是重要的内容,包括经验性抗生素治疗和目标性抗生素治疗.除此之外,脑脊液引流、去除人工材料等外科手段也扮演重要角色.鉴于颅内感染的高发病率和高致死率,笔者对神经重症患者颅内感染的诊断方法和治疗手段等进行系统总结,呼吁应采取有效手段积极预防颅内感染的发生,并在医疗区域内建立有效的监督和反馈机制,以降低颅内感染的发生率.

abstractsIntracranial bacterial infection is a common and serious complication in patients with critical neurological diseases.It has a high mortality rate and has adverse effect on the prognosis of patients.For intracranial infection,the application of antibiotics is still an important part,including empirical antibiotic therapy and targeted antibiotic therapy.In addition,cerebrospinal fluid drainage,removal of artificial materials and other surgical methods also play important roles.In view of the high incidence and mortality of intracranial infection,we systematically summarize the diagnosis and treatment of intracranial infection in patients with critical neurological diseases,call for effective measures to prevent intracranial infection and establish effective monitoring and feedback mechanism in the medical wards to reduce the incidence of intracranial infection.