摘要皮肤、肌肉、骨及神经等组织损伤可对机体造成不同程度的损害，严重时导致器官功能障碍，甚至危及生命。为恢复受损组织的结构和功能，各种免疫细胞和组织细胞先后参与了组织修复过程。中性粒细胞作为终末分化的白细胞，在组织损伤发生后可通过吞噬作用及分泌抗菌物清除病原体和组织碎片，为后续的组织修复创造条件，但是过度的中性粒细胞募集和炎症反应可能加重组织损伤。近年来有研究表明，中性粒细胞存在异质性和可塑性，并且在启动组织修复、促进血管生成、调节细胞增殖等方面均发挥着重要作用。笔者就中性粒细胞在组织修复中的募集、表型与功能、修复作用及结局进行综述，为后期相关研究提供参考。

abstractsDamage to skin, muscle, bone and nerve tissues can result in various degrees of damage to the body, leading to organ dysfunction even life-threatening. To restore the structure and function of the damaged tissues, various immune cells and histocytes have successively participated in the tissue repair process. As the terminally differentiated white blood cells, neutrophils can remove necrotic tissue, debris and pathogens via phagocytosis and release of antimicrobial peptides after tissue injury to provide conditions for subsequent tissue repair process. However, enhanced neutrophils recruitment as well as excessive inflammatory response may also aggravate tissue damage. In recent years, more and more evidences indicate that neutrophils display plasticity and heterogeneity and that play critical roles in the initiation of tissue repair, promotion of angiogenesis, regulation of cell proliferation and so on. Herein, the authors review the recruitment, phenotype and function, role and outcome of neutrophils during tissue repair so as to provide references for future studies.