摘要采用经食管超声心动图技术在冠状动脉造影检查证实为冠状动脉正常者11例和32例冠心病患者中,探测了胸主动脉粥样硬化性病变并计算了动脉粥样硬化总积分(TAS)和硬化指数(β).结果:TAS或β值与冠状动脉粥样硬化之间有密切关系,随冠脉病变支数的增加,TAS和β值也明显增高,这为无刨性估测冠状动脉粥样硬化开辟了新的途径.

abstractsThoracic aorta was performed in 11 normal subjects and 32 patients with coronary artery disease by transesophageal echoeardiography(TEE).All subjects had undergone diagnostic cardiac catheterization including coronary angiography 32 patients were with obstructive coronary artery stenosis which was defined as either＞75% narrowing of the luminal diameter in at least one of the left anterior descending,lef,circumflex or right coronaries or＞50% stenosis of the left main coronary,including 12 single-vessel disease(SVD),12 double-vessel disease(DVD)and 8 triple-vessel disease(TVD).The total ahterosclerosis score(TAS)and the stiffness index(β)of the descending thoracic aorta were calculated from TEE for evalualing the atherosclerosis of the thoracic aorta.The result showed that TAS and β were significantly higher in patientS with coronary artery disease than those in normal control subjects(P＜0.05).There were close relation between the TAS or β and the extent of coronary artery disease(r=0.71,r=0.57,respectively),This study indicates that detection of atherosclerotic plague in the thoracic aorta by TEE is useful in the noninvasive prediction of the presence and severity of coronary artery disease.