摘要目的 应用血管回声跟踪(echo-tracking,ET)技术研究影响正常人及2型糖尿病患者下肢动脉弹性的相关危险因素.方法 选取30例正常人和68例2型糖尿病患者,应用ET技术检测股总动脉、腘动脉弹性指标:僵硬度指数(β).比较正常对照组及糖尿病组一般情况及生化指标的差异,并对影响β值的相关危险因素如年龄、血压、血脂指标采用简单线性回归及多无线性回归方法进行分析.结果 正常对照组及糖尿病组股总动脉、腘动脉的β值与年龄、收缩压有良好的相关性(P<0.05).糖尿病组股总动脉的β值与甘油三酯、低密度脂蛋白、载脂蛋白B、脂蛋白a有良好的相关性(P<0.05),胭动脉的β值与血脂指标相关性不明显(P>0.05).结论 2型糖尿病患者随着年龄、血压、血脂的升高,动脉僵硬度增加,弹性减低.

abstractsObjective To analyze risk factors of elasticity of common femoral artery(CFA)and popliteal artery(PoA)in type 2 diabetic(T2DM)patients by echo-tracking(ET)technique.Methods Thirty healthy subjects(control group)and sixty-eight T2DM patients were enrolled in this study.The stiffness β of common femoral and popliteal artery were automatically measured by ET technique.The differences in ordinary and biochemical indices between control group and T2DM group were compared and analyzed by the method of linear regression and multiple linear regression.Results In both control and the T2DM group,β of CFA and PoA were significantly correlated with age,systolic blood pressure.TC, LDL,ApoB and LPa of CFA were also significantly correlation with β in T2DM group(P<0.05).Conclasions The stiffness of CFA and PoA in patients with T2DM increased followed by the increase of age, systolic blood pressure,TC,VLDL,ApoB and LPa.