摘要目的 应用左心房容积追踪(left atrial volume tracking,LAVT)技术探讨原发性高血压(essential hypertension,EH)早期患者左心房功能变化.方法 早期EH组30例,正常对照组35例.存储心尖四腔、两腔观3个心动周期的动态二维图像,应用EUB-6500超声诊断仪,于左房追踪模式下分别描记出四腔、两腔观左房内膜后,系统自动获取左房容积曲线,记录左房最大容积(LAVmax)、心电图P波对应的左房容积(LAVp)、左房最小容积(LAVmin),用体表面积(BSA)Xff各容积值进行标化(LAVImax,LAVIp,LAVImin),再计算左房被动、主动及整体排空容积(LAVIpass,LAVIact,LAVItotal)以及左房被动、主动、整体排出率(%LAVIpass,%LAVIact,%LAVItotal),有效左房被动、主动排出率(%eLAVIpass,%eLAVIact)及左房被动与主动排出量比值(LAVpass/act).结果 与正常对照组相比,早期EH组LAVIp、LAVIact、LAVItotal、%LAVIact、%LAVItotal、%eLAVIact显著增加,而LAVIpass、%LAVIpass、%eLAVIpass,LAVIpass/act显著降低,差异均具有统计学意义(P＜0.05或P＜0.01).结论 早期EH患者的左房容积变化以舒张晚期左房主动排出量增多为主,即左房主动作功代偿增加,LAVT技术能敏感、准确地评价左心房功能.

abstractsObjective To evaluate left atrial(LA)function in patients with prophase essential hypertension (EH)by left atrial volume tracking(LAVT)method.Methods Thirty prophase EH patients and 35 healthy subjects(control group)were enrolled in this study.Ultrasound LAVT(Hitachi EUB-6500)was applied to display and analyze the LA volume loop imaging on the standard LV apical two and four chamber views.The maximal LA volume at end-systole(LAVmax),LA volume at the onset of ECG-P wave(LAVP),the minimal LA volume at end-diastole(LAVmin)from the LA volume loop were recorded,and body surface area was used to revise these volume indexs(LAVImax,LAVIp,LAVImin).LA pass,act and total empting volume(LAVIpass,LAVIact,LAVItotal)and empting rate(%LAVIpass,%LAVIact,%LAVItotal),effective pass and act erupting rate(%eLAVIpass,%eLAVIaet),and the proportionality of pass empting volume and act empting volume were caculated.Results The LAVIp,LAVIact,LAVItotal,%LAVIact,%LAVItotal,%eLAVIact in the prophase EH group were significantly higher than those in the control group,wheras the LAVIpass,%LAVIpass,%eLAVIpass,LAVIpass/act were lower(all P＜0.05,or P＜0.01).Conclusions The LA volume change in prophase EH is the act empting volume increased at end-diastole in main,LAVT is a potientially useful tool to evaluate the function of LA.