摘要目的 对比观察超声引导经皮注射聚桂醇与无水乙醇硬化治疗肝、肾单纯性囊肿的疗效与不良反应.方法 对55例肝、肾单纯性囊肿进行超声引导下穿刺抽液、生理盐水清洗囊腔后注入聚桂醇进行硬化治疗(A组),观察与记录治疗过程中患者的不良反应及术后3个月所治囊肿的超声影像表现;回顾分析60例肝、肾单纯性囊肿无水乙醇硬化治疗(B组)的术中不良反应及术后3个月原囊肿的超声影像表现.结果 A组不良反应率为5.5％,程度仅为穿刺部位轻度不适感;B组不良反应率为20％,程度为轻度～中度的腹痛或醉酒表现.A组总有效率100％,治愈率78.2％;B组总有效率100％,治愈率78.3％.结论 聚桂醇对肝、肾单纯性囊肿的硬化治疗效果与无水乙醇几近一致,但副反应极少,患者对其耐受性明显优于无水乙醇.

abstractsObjective To make a comparative assessment on both the therapeutic effects and side effects between percutaenous lauromacrogol injection therapy(PLIT) and percutaenous ethanol injection therapy(PEIT) for simple hepatic or renal cyst.Methods In group A,55 patients with simple hepatic or renal cysts underwent ultrasound-guided aspiration and successive PLIT.The intra-operative side effects were investigated and the therapeutic effects assessment by using ultrasonography was conducted 3 months after the treatment.In group B,60 patients with simple hepatic or renal cysts had received ultrasound-guided aspiration and PEIT sometime before.The intra-operative side effects and therapeutic effects on the thirdmonth ultrasonography were independently reviewed according to their case records.Results In group A,3 patients(5.5 ％) expressed slight discomfort but not pain while receiving lauromacrogol injection.Follow-up ultrasound examination at the end of third month demonstrated the cysts in 43 patients completely regressed,while cysts in rest 12 patients shrank over 50 ％ in size,showing the overall response rate(ORR) and completely cure rate(CCR) were 100％ (55/55) and 78.2％ (43/55) for PLIT respectively.In group B,12 patients(20％) suffered from slight to moderate irritating pain or drunk performance.The third-month ultrasound examination disclosed that cysts in 47 patients completely vanished,and cysts in the other 13patients shrank more than a half,indicating the ORR and CCR were 100％ (60/60) and 78.3 ％ (47/60) for PEIT respectively.Conclusions Although their therapeutic efficacy are perfectly similar,PLIT is much more superior to PEIT in term of less and minor side effects.