摘要目的 研究高血压视网膜病变患者视网膜背向散射积分(IBS)值的改变,为临床判断高血压病眼底改变提供新的参考依据.方法 选取缓进型高血压病患者100例(100只眼),根据临床高血压视网膜病变分期分为4组:①Ⅰ级,28例(28只眼);②Ⅱ级,27例(27只眼);③Ⅲ级,24例(24只眼);④Ⅳ级,21例(21只眼).正常对照组30例(30只眼),测量每位受检者鼻侧视网膜IBS值,并计算校正IBS值(IBS%).结果 随着高血压视网膜病变病程的进展,视网膜IBS值(29.48±0.09,32.50±0.04,34.62±0.39,36.48±0.46,37.52±0.43)和IBS%[(68.50±2.11)%,(72.03±0.57)%,(74.29±0.77)%,(76.06±1.43)%,(77.45±0.75)%]依次增加,除Ⅲ级组与Ⅳ级组外,各组相比差异均有统计学意义(均P=0.000).结论 随着病程进展,高血压病患者视网膜IBS值和IBS%逐渐增高,背向散射积分可作为评价高血压视网膜病变患者视网膜改变的有效方法.

abstractsObjective To investigate the integrated backscatter(IBS) changes of retina in hypertensive disease patients to offer the reference to clinician for ocular fundus changes of hypertensive disease.Methods One hundred chronic hypertension patients (100 eyes) were divided into 4 groups by clinical stages:① gradeⅠ,28 persons (28 eyes);② grade Ⅱ,27 persons (27 eyes);③ grade Ⅲ,24 persons (24 eyes);④ grade Ⅳ,21 persons (21 eyes).Thirty normal persons of 30 eyes were the control group.Their IBS values were measured on nose side of retina,and the correction IBS values(IBS%) were calculated.Results With the deterioration of hypertensive disease,the IBS(29.48±0.09,32.50±0.04,34.62±0.39,36.48±0.46,37.52±0.43) and IBS%[(68.50±2.11)%,(72.03±0.57)%,(74.29±0.77)%,(76.06±1.43)%,(77.45±0.75)%] of retina were gradually increased.The statistical difference were found among various groups(P=0.000).Conclusions With the deterioration of hypertensive retinopathy,the IBS and IBS% increased gradually.The IBS technique is a useful method to assess the retinopathy of hypertension.