摘要目的 探讨双源CT双能量血管成像(DE-CTA)对颈内动脉海绵窦瘘(CCF)的诊断价值.方法 选择14例临床疑诊CCF的患者进行DE-CTA.利用直接能最减影后的数据进行去骨图像重组,同时将能量平均后数据进行非去骨图像重组.由4名多年从事脑血管疾病影像诊断的放射科医师独立分析图像,其中2名评价颈内动脉海绵窦段DE-CTA的图像质量,2名评价瘘口位置、数量、大小及有无异常的颅内静脉扩张,比较各种后处理方法对CCF瘘口及相关病变的显示情况.利用Kappa检验分析2名医师对图像质量评价的一致性.利用t检验及相关性分析评价去骨与非去骨重组图像测得的瘘口大小.结果 14例患者28条颈内动脉颅内段均可以满足影像评价标准.14例患者经行双能量直接去骨颅脑CTA检查均确诊为CCF,其中,病变位于双侧2例,左侧7例,右侧5例.14例患者共16处病变,非去骨及去骨重组图像均发现瘘口16处.去骨及非去骨重组图像测得瘘口的平均大小分别为(0.36±0.10)、(0.35±0.11)mm,两者差异无统计学意义(t=0.29,P＞0.05),且二者测量值之间有很好的相关性(r=0.97,P＜0.05).去骨重组图像发现8例患者13支大脑皮质静脉扩张,非去骨重组图像仅发现6例患者9支大脑皮质静脉扩张.结论 DE-CTA图像多种重组方法相结合对CCF的诊断和治疗方案的制定具有重要价值.

abstractsObjective To explore the clinical value of dual-energy CT angiography (DE-CTA) in the diagnosis of carotid cavernous fistula. Methods Fourteen patients suspected of carotid cavernous fistula underwent DE-CTA between Dec. 2008 and Feb. 2010. Image post-processing of DE-CTA was performed with the dedicated software to obtain bone-removal and non bone-removal images. Four experienced radiologists evaluated image quality of DE-CTA, the number, location and size of fistulae and dilation of cerebral veins. The bone-removal and non bone-removal images were compared for displaying of fistulae and other related lesions. Kappa test was used to test the consistency of image quality evaluation between two radiologists. The sizes of fistulae were measured with bone-removal DE-CTA images and non bone-removal DE-CTA images respectively and their results were compared by using student's t-test and the correlation test. Results Twenty-eight intracranial internal carotid arteries of 14 patients showed acceptable image quality. Fourteen cases were diagnosed as carotid cavernous fistula with both bone-removal and non boneremoval DE-CTA images. Two patients presented with bilateral lesions, while 7 patients presented with left lesions and 5 patients had right lesions. Totally, sixteen fistulae lesions were detected in 14 patients. The mean size of fistulae was (0. 36 ±0. 10) mm by bone-removal images, whereas (0. 35 ±0. 11 ) mm by non bone-removal images. There was no significant difference between the two methods ( t = 0. 29, P ＞ 0. 05 ),and good correlation was found between the two methods ( r = 0. 97, P ＜0.05). Thirteen dilated cerebral veins in 8 cases were found by bone-removal images versus 9 dilated cerebral veins in 6 cases by non boneremoval images. Conclusions Image post-processing of DE-CTA is a simple and useful method to identify carotid cavernous fistula. DE-CTA is also useful for therapeutic planning.