摘要目的 研究用热释光剂量计(TLD)方法核查放射治疗参考条件和非参考条件下剂量学参数的可靠性验证.方法 在参考条件和非参考条件下,用建立的TLD方法,核查5家医院的10条6 MV光子线束剂量随深度、源皮距离、照射野大小和45°楔形板等变化,5条9 MeV电子线束轴向最大剂量点处等剂量学参数,TLD估算结果与剂量仪测量结果进行对比.结果 6 MV光子线束轴上非参考条件和离轴非参考条件下的TLD监测结果与指型电离室监测结果的相对偏差范围分别为-1.7％ ～5.4％、-6.3％～-0.6％,符合IAEA要求的≤±7％;电子射线束TLD估算结果与平行板电离室测量结果相对偏差范围为-2.3％ ～3.7％,符合IAEA要求的≤±5％.结论 用TLD核查参考条件和非参考条件下放射治疗剂量学参数方法可靠,简单易行.

abstractsObjective To verify the methodology for auditing dosimetric parameters in reference and non-reference conditions with thermoluminescent dosimeters (TLDs).Methods Under reference and non-reference conditions,the established TLD methods were used to observe the absorbed dose variations with depth,SSD,field size and 45 wedges for 10 photon beams at 5 hospitals.Dosimetric parameters,including doses at Dmax points in axis,on 5 electron beams of 9 MeV were measured.The measurement results were compared between the TLDs and plane parallel ionization chambers.Results For 6 MV photon beams,the relative deviation of between finger ionization chamber method and TLD chips was in the range of-1.7％ to 5.4％ under on-axis non-reference conditions,and-6.3％ to-0.6％ under off-axis non-reference conditions,respectively,all within the range of ≤ ± 7％ as required by the IAEA.The relative deviation between plane parallel chamber and TLD method was-2.3％ to 3.7％,within ± 5％ as required by the IAEA.Conclusions It is convenient and feasible to use TLD method for quality audits of dosimetric parameters in radiotherapy.