摘要乳腺癌内乳区淋巴结照射能够降低局部和远处复发并改善患者的生存,NCCN指南也在内乳区淋巴结照射方面进行了相应的更新,但由于内乳区淋巴结照射造成的心肺损伤不容忽视,因此需要提供更为准确的个体化内乳区放疗指征.内乳区前哨淋巴结活检能够以微创的方法评估内乳区淋巴结的转移情况,为内乳区淋巴结照射提供准确的放疗指征,使乳腺癌患者获得更大的生存获益.本文主要从内乳区放疗获益、不良反应控制及内乳区前哨淋巴结活检指导放疗的探讨等方面进行了综述.

abstractsInternal mammary lymph node irradiation (IMLNI) could reduce local recurrence and distant recurrence and improve survival.The NCCN Guidelines have updated the recommends in IMLNI.However, the relative toxicities of IMLNI to the heart and lungs should be carefully considered by clinicians, so individualized indications for IMLNI are needed.Internal mammary sentinel lymph node biopsy (IM-SLNB) could be an accurate technique to guide IMLNI with minimally invasive staging, and provide more survival benefits to patients.This article reviews the benefits of IMLNI, controls of the side effect, and discussion of IMLNI guided by IM-SLNB.