摘要脉络丛癌是起源于脑室内脉络丛上皮细胞的较罕见的颅内原发肿瘤,为WHOⅢ级,多发生于儿童.其治疗策略以最大程度的安全手术切除为主,对术后辅助治疗的疗效一直存在争议.近年来研究提示对于次全切除的脉络丛癌患者,术后联合放疗、化疗可改善预后,延长生存.经检索近15年相关文献,就脉络丛癌的诊疗现状及研究进展进行综述.

abstractsChoroid plexus carcinoma is a relatively rare primary intracranial malignant tumor which is derived from the choroid plexus epithelium.It is classified as World Health Organization (WHO) grade Ⅲ and mainly occurs in children.Currently,maximal surgical resection is still the main therapeutic strategy.The clinical efficacy of postoperative adjuvant therapies remains controversial.Recent studies have promoted that postoperative combination of radiotherapy and chemotherapy can enhance the clinical prognosis and prolong the survival time for choroid plexus carcinoma patients undergoing sub-radical resection.In this review,relevant articles published in the recent 15 years were retrieved to summarize the current status and research progress on the diagnosis and treatment of choroid plexus carcinoma.