声门上型喉癌根治性放疗颈部预防照射的靶区勾画
Delineation of prophylactic cervical target volumes in radical radiotherapy for supraglottic laryngeal carcinoma
摘要调强放疗是喉癌的主要治疗手段之一,而新版国际共识中喉癌颈部预防照射的靶区勾画仅以N分期进行推荐,未考虑解剖分型、临床分期、病理分化程度等其他临床因素的影响,而且部分颈部靶区勾画范围也存在争议。本文参考颈部外科手术的数据,重点综述声门上型喉癌颈部淋巴结转移规律的相关临床研究,总结声门上型喉癌颈部阳性淋巴结分布特点及影响因素,为根治性放疗中颈部预防照射的精准靶区勾画提供参考。
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abstractsIntensity-modulated radiotherapy (IMRT) is one of the primary treatments for laryngeal cancer. According to the latest international guidelines, the delineation of lymphatic clinical target volumes (CTV) is performed only on the basis of N stage without considering other impact factors, such as tumor subsite, clinical stage and histopathological differentiation. Besides, the detailed lymph node regions that should be included in CTV are still controversial. In this article, clinical data of cervical surgery were retrospectively analyzed, clinical trials associated with lymph node metastases of supraglottic laryngeal carcinoma were reviewed, the distribution characteristics and risk factors of positive lymph nodes were summarized, aiming to provide reference for the precise delineation of prophylactic CTV in radical radiotherapy for supraglottic laryngeal carcinoma.
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