摘要皮肤T细胞淋巴瘤是一组相对罕见的主要表现在皮肤的成熟T细胞淋巴瘤，其常见的亚型是蕈样肉芽肿（俗称蕈样霉菌病）。电子线全身照射作为重要的常规治疗手段之一，却存在着剂量分布不均、体位重复差、治疗时间过长等诸多缺点，从而影响疗效及患者预后。近年随着螺旋断层放疗系统的出现与逐步普及，越来越多的单位凭借其能治疗超长靶区和实现剂量雕刻式分布的特点，正逐步扩展其在全身皮肤照射治疗中的应用，以便进一步探讨其优劣并确认是否能取代传统电子线全身照射。本文对螺旋断层全身皮肤照射治疗的研究进展做一综述，介绍其治疗技术的发展、临床治疗效果及目前存在的顾虑和争议。

abstractsCutaneous T-cell lymphomas are a relatively rare group of mature T-cell lymphomas mainly manifesting in the skin, and its common subtype is mycosis fungoides. Total skin electron irradiation is one of the important conventional treatment methods, but there are many disadvantages, such as uneven dose distribution, poor position repetition, and long treatment time, which affect the clinical efficacy and patient prognosis. With the emergence and gradual popularization of helical tomotherapy in recent years, more and more medical institutions are gradually expanding their applications in total skin irradiation due to their ability to treat ultra-long targets and achieve dose-sculpted distribution, aiming to further explore its good or bad, and confirm whether it can replace the traditional total skin electron irradiation. In this article, research progress on total skin irradiation using helical tomotherapy was reviewed, the development of treatment technology, clinical efficacy and current concerns and controversies were illustrated.