摘要肝门部胆管癌是一种来源于左右肝管、肝总管及其汇合部位的恶性肿瘤.由于该疾病本身的侵袭特性以及除了手术切除外尚缺少其他有效的治疗措施,故其仍然是外科领域的一个挑战.肝门部胆管癌的诊断主要依靠临床表现、肿瘤标记物及影像学技术.此外,关于术前是否行引流以及如何选择合理的治疗手段才能使患者最大获益等方面仍存在较大争议.本文对近年来肝门部胆管癌的诊疗进展做一综述,以期为临床治疗提供理论依据和新的思路.

abstractsHilar cholangiocarcinoma is a malignant disease in the main left or right hepatic ducts,ductus hepaticus communis or their confluence.The treatment for hilar cholangiocarcinoma remains a challenge because of the aggressive nature of the disease and the absence of effective treatments besides surgical resection.Hilar cholangiocarcinoma is diagnosed by its clinical manifestations,tumor markers and results of imaging studies.Problems as the necessity of preoperative hepatic bile drainage and decision making of proper treatment remain controversial.Here,we will review the current advances in the management of hilar cholangiocarcinoma,so as to provide theoretical basis and new ideas for clinical treatment.