摘要目的 从文献计量学角度分析高压氧(hyperbaric oxygen,HBO)研究热点及研究前沿.方法 以科学引文数据库(Web of Science,WoS)为数据源,检索2006-2015年收录的HBO相关文献,对文献发表年份进行统计分析,同时运用CiteSpace信息可视化软件进行关键词共现分析,探索HBO的研究热点和研究前沿.结果 检索获得2 865篇HBO相关文献.2006-2015年HBO累积发文量呈线性增长趋势.研究热点呈现如下特点:从内容上看,热点主题有氧化应激、凋亡等关于HBO作用机制的基础研究,以及一氧化碳中毒、脑缺血、坏死性筋膜炎、放射性坏死、减压病、糖尿病足部溃疡和伤口等关于HBO实际应用的临床研究;从时间上看,研究在2006-2011年处于热点涌现期,2011-2013年进入热点休眠期,2013-2015年为平稳发展期.结论 HBO研究处于成熟期,HBO在伤口中的临床应用及相关的基础研究将是HBO研究方向.

abstractsObjective To analyze research hot spots and frontiers in hyperbaric oxygen (HBO) from the perspective of bibliometrics.Methods Relevant data concerning HBO from 2006 to 2015 were retrieved by using Web of Science (WoS) as the database,and statistical analyses were made on the literature published within the said span of years.At the same time,the information visualization software CiteSpace was used for kevword.s co-occurrence analysis,with an aim to find out research hot spots and frontiers in HBO.Results 865 related papers concerning HBO were retrieved,and analysis showed that the accumulated amount of published papers on HBO from 2006 to 2015 displayed an increasing trend.Research hot spots concerning HBO displayed the following features:from the perspective of contents,research hot spots covered such basic research topics as oxidative stress,apoptosis and related mechanisms involved,as well as clinical researches on its practical applications in CO intoxication,cerebral ischemia,necrotic fasciitis,radioactive necrosis,decompression sickness,diabetic foot ulcer and wound treatment.From the standpoint of time,research results revealed that the years from 2006 to 2011 were hot emergence period,the years from 2011 to 2013 were hot dormant period,and the years from 2013 to 2015 were steady development period.Conclusions HBO research is in a mature stage.Clinical application of HBO in wound care and related basic research will be the chief research direction of HBO.