摘要目的 探讨长航对不同年龄和工龄船员航行前后血清激素水平的影响.方法 采集某舰船人员航行前后的血清样本,用Elisa试剂盒检测航行前后81名舰船人员血清中总甲状腺素(thyroxine,T4)、总三碘甲状腺原氨酸(triiodothyronine,T3)、甲状腺刺激激素(thyroid stlmulating,TSH)、促肾上腺皮质激素(adreno-cortico-tropic-hormone,ACTH)、促肾上腺皮质激素释放素(corticotropin-releasing hormone,CRH)、皮质醇(cortisol,COR)、睾酮(testosterone,T)、神经肽Y(neuropeptide Y,NPY)8种激素含量,分别按年龄和舰船上工龄对船员进行检测结果的分层对比分析.结果 低年龄组(24 ～ 29岁)和高年龄组(≥30岁)的比较中,低年龄组船员血清激素水平发生明显变化的有2项(P＜0.05),高年龄组船员血清激素水平发生明显变化的有6项(P＜0.05).低工龄组(2～8年)和高工龄组(≥9年)的比较中,低工龄组船员血清激素水平发生明显变化的有2项(P＜0.05),高工龄组船员血清激素水平发生明显变化的有4项(P＜0.05).结论 长航对年龄小、工龄短的舰船人员航行中血清激素水平的影响比年龄大、工龄长的舰船人员小.

abstractsObjective To investigate the effects of prolonged deloyment at sea on the serum hormone levels of the ship crew with different age and length of sea service before and after deployment at sea.Methods Serum levels of thyroxine (T4),T3 (triiodothyronine),thyroid stlmulating (TSH),adreno-cortico-tropichormone (ACTH),corticotropin-re-leasing hormone (CRH),COR (cortisol),testosterone (T) and neuropeptide Y (NPY) were detected by ELISA,and the obtained results were analyzed and compared according to age and length of service.Results When the low-age (age range between 24 and 29) group was compared with the senior age (over 30 years) group,there were 2 serum hormones in the low-age group that displayed significant changes (P ＜0.05),while there were 6 hormones in the senior age group that displayed significant changes (P ＜ 0.05).When comparisons were made between the short length of service group (from 2 to 8 years) and the long length of service group (≥9 years),there were 2 serum hormones in the shorter length of service group that displayed significant changes (P ＜ 0.05),as compared with 4 serum hormones that showed obvious changes in the longer length of service group (P ＜ 0.05).Conclusions Results indicated that the effects of prolonged deployment at sea on serum hormone levels on the low-age and shorter length of service group were lower than those in the senior-age and longer leigth of service group.