摘要目的:通过调查结直肠息肉患者小肠细菌过度生长(SIBO)的发生情况，分析其与结直肠息肉的关系。方法:将2018年9月至2021年3月就诊于解放军总医院第六医学中心消化内科行结肠镜检查的患者按就诊顺序入组，根据结肠镜下诊断分为观察组(结直肠息肉组，300例)和对照组(无息肉组，150例)，所有患者完善甲烷氢呼吸检查，比较2组SIBO发生情况。将观察组患者根据结直肠息肉数目、部位、大小、病理类型进一步细分，比较各亚组的SIBO患病率。结果:观察组患者SIBO发生率(217/300，72.3%)明显高于对照组(58/150，38.7%)，差异有统计学意义( P<0.01)；不同结直肠息肉数目、部位、大小、病理类型之间的SIBO发生率比较差异无统计学意义( P>0.05)。 结论:SIBO有助于结直肠息肉的发生，SIBO患者及时清菌对预防结直肠息肉与结直肠癌的发生具有重要意义。

abstractsObjective:To investigate small intestinal bacterial overgrowth (SIBO) in patients with colonic polyps and analyze the correlation between them.Methods:The patients who received colonoscopy in the Department of Gastroenterology of the Sixth Medical Center of Chinese PLA General Hospital from September 2018 to March 2021 were enrolled in the order of visits and divided into observation group (polyp group, 300 cases) and control group (non-polyp group, 150 cases) according to the results of colonoscopy. All the patients received hydrogen/methane breath test for comparing the development of SIBO. Then the patients were further subgrouped by polyp’s number, site, size, and pathological type, for comparing the prevalence of SIBO in each group.Results:The prevalence of SIBO in the polyp group (217/300, 72.3%) was obviously higher than that in the control group (58/150, 38.7%) ( P<0.01); there was no significant difference in the prevalence of SIBO among different subgroups of polyp’s number, location, size, and pathological type ( P>0.05). Conclusion:SIBO is one of the risk factors for colonic polyps. Timely treatment of SIBO patients by cleaning bacteria is essential to prevent the occurrence and recurrence of colonic polyps and colonic cancer.