摘要近年来,对于DTC治疗反应评价的研究日益深入.2015年ATA指南中首次提出 "治疗反应评估体系"的定义,其主要倡导动态监测、持续评估、及时更新疾病危险分级的治疗反应评估理念,修正了以往体系以病理学特征为主的静止性、单次定性评估的不足,将手术等治疗干预对预后的影响纳入动态评估及风险分层体系,为推进患者个体化治疗提供了循证依据.如何解读并实施该治疗反应评估体系,成为国内外关注的焦点.现就DTC治疗反应评估体系近年来的更新进行简要综述及解读.

abstractsRecent research has gained much depth and details on the response-to-therapy assessment system (RTAS) of DTC. The concept of RTAS was first proposed in the 2015 ATA guidelines, mainly advocating dynamic and ongoing assessment of a disease process after primary therapy is completed. This recommendation is to compensate for the deficiency of a static, single-parametric evaluation system that is conventionally pathology-dominated. The concept of risk-adaptive management has been adopted in individual decision-making processes, so as to tailor treatment plans accordingly with an understanding that therapies (e.g. surgery, etc.) should also be involved as a continuum of risk assessment. The RTAS according to the new guidelines has been clearly highlighted worldwide. This review aims to outline the progress and latest update of RTAS on DTC.