摘要目的:分析2013至2022年国家自然科学基金委员会(NSFC)在核医学与分子影像领域各类项目申请与资助情况，探讨该领域基础研究及临床转化面临的挑战。方法:回顾性收集2013至2022年NSFC医学科学部五处申请与资助的核医学与分子影像领域(二级代码H2704、H2706)各类项目数据资料，分析该领域各类项目申请数量、资助数量、资助方向、资助强度、依托单位分布情况及研究热点等。结果:2013至2022年，NSFC共接收核医学与分子影像领域各类项目申请5 397项，总资助数量899项，申请与资助数量呈稳步增长趋势。整体资助强度从2013年的4 893.50万元增长至2022年的5 949.54万元，增幅21.58%。在所有依托单位中，上海交通大学在申请数量(440项)和资助数量(82项)上位居首位，厦门大学在整体资助率上位居首位(25.42%，30/118)，北京大学的总资助金额最高(4 189.71万元)。研究热点聚焦于肿瘤靶向分子探针的构建和肿瘤内部分子成分的精准显像等。结论:近10年NSFC在核医学与分子影像领域的资助项目数及总经费稳步增长，资助项目种类多样、学科交叉广泛，推动了我国核医学与分子影像学科的创新发展。

abstractsObjective:To analyze the application and funding status of various projects of nuclear medicine and molecular imaging supported by the National Natural Science Foundation of China (NSFC) from 2013 to 2022, and explore the challenges faced by basic research and clinical transformation in this field.Methods:From 2013 to 2022, application and funding information of nuclear medicine and molecular imaging projects (secondary code H2704, H2706) from five departments of Medical Science Department of NSFC were retrospectively collected. The number of applications, number of funding, funding direction, funding intensity, distribution of supporting units and research hotspots of various projects in this field were analyzed.Results:From 2013 to 2022, the total number of applications of various projects in the field of nuclear medicine and molecular imaging reached 5 387, and the total number of grants reached 899. The number of applications and grants showed a steady growth trend. The overall funding intensity increased from 48.935 0 million yuan in 2013 to 59.495 4 million yuan in 2022, with the increase of 21.58%. Among all supporting units, Shanghai Jiao Tong University topped the list for both the number of applications (440) and the number of grants (82), Xiamen University ranked the first in terms of overall funding rate (25.42%, 30/118), and Peking University ranked the first in terms of total funding intensity (41.897 1 million yuan). Research hotspots focused on the construction of tumor targeted molecular probes and precise imaging of tumor internal molecular components.Conclusion:In the past decade, the number of related projects and total funding of nuclear medicine and molecular imaging supported by NSFC have steadily increased, and the types of funded projects are diverse and interdisciplinary, promoting the innovative development of nuclear medicine and molecular imaging disciplines in China.