摘要光声成像结合了传统光学成像和超声成像的优点，具有高的空间分辨率和成像对比度，可以从宏观、介观、微观3个层面实时采集分子信息并提供高特异性的组织影像。光声成像已成功应用于乳腺癌的临床诊断研究，其在乳腺癌的早期筛查、良恶性诊断、不同病理类型及分子亚型鉴别、治疗效果监测和肿瘤边缘评估以指导手术等方面均有明显的优势。该文综述了光声成像相对于常规乳腺成像方式在乳腺癌检测中的优势及临床研究的进展。

abstractsPhotoacoustic imaging combines the advantages of conventional optical imaging and ultrasound imaging with high spatial resolution and imaging contrast that can capture molecular information from macroscopic, mesoscopic and microscopic levels in real time and provide highly specific tissue images. Photoacoustic imaging has been successfully applied to the study of clinical diagnosis of breast cancer. It has significant advantages in early detection of breast cancer, benign and malignant diagnosis, identifying different pathological types and molecular subtypes of diagnosis, monitoring the effect of anti-cancer treatment and assessing tumor margins to guide surgery. Based on the published data of clinical researches, this review summarizes the advantages of photoacoustic imaging over conventional breast imaging modalities in breast cancer detection and the progress of clinical studies.