摘要口腔种植体与周围软组织形成良好的结合对保证种植修复的长期效果至关重要。本文综述了口腔种植体周软组织结合的研究进展，重点介绍了基于免疫微环境管控的种植体穿龈界面改性方法。该方法通过调节种植体表面性质，影响种植体周围免疫反应，从而增强种植体与软组织的结合。本文旨在为口腔种植领域的相关研究及临床应用提供参考。

abstractsA good integration of dental implants and the surrounding soft tissue is essential to ensure the long-term effect of implant. In this review, we summarized the research progress of peri-implant soft tissue integration of dental titanium implants, with emphasis on the modification of the gingival interface of implants based on immune microenvironment regulation. This method influences the immune response around the implant by promoting the surface properties of implants, so as to enhance the peri-implant soft tissue integration. The purpose of this review is to provide reference for the related research and clinical application in the field of dental implantation.