摘要脓毒症是宿主对感染的反应失调引起的危及生命的器官功能损害.临床上病原学培养和鉴定结果时间长、阳性率低,因此寻找能够早期诊断、并进行预后和治疗评价的生物学标志物尤为重要.本文重点综述了促炎性细胞因子、抑制炎症反应的细胞因子和天然免疫系统的免疫细胞表面受体等在脓毒症中的诊断价值.
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abstractsSepsis is now defined as life-threatening organ dysfunction due to a dysregulated host response to infection.The identification of pathogen is usually time-consuming.Besides, it has a low positivity rate in diagnosis of sepsis.Thus, it’s crucial to find suitable biomarkers for early diagnosis , prognosis and evaluation of treatment effect of sepsis.This article reviews the diagnostic value of pro-inflammatory cytokines, anti-inflammatory cytokines,surface receptors of immune cells in nature immunity in sepsis.
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