摘要目的:探讨经鼻高流量湿化氧疗治疗急性群发性窒息性气体中毒合并肺大泡患者的观察与护理。方法:回顾性分析2019年6月收治的5例经鼻高流量湿化氧疗的急性群发性窒息性气体中毒伴肺大泡患者的护理资料，观察患者的氧合指数、气道湿化、病情转归的情况。结果:5例患者均顺利经鼻高流量湿化氧疗后顺利过渡为鼻导管吸氧，均未插管，出院时未吸氧状态下pH：7.36~7.42，PO 2：82~106 mmHg，PCO 2：32~39 mmHg，白细胞、心肌酶均正常，并无脑部损伤及鼻周皮肤破损和腹胀的发生。 结论:经鼻高流量湿化氧疗能够有效的提高急性群发性窒息性气体中毒合并肺大泡患者氧疗效果。

abstractsObjective:To explore the observation and nursing of patients with acute mass asphyxia poisoning with pulmonary bullae treated by nasal high-flow humidification and oxygen therapy.Methods:Review and summarize the data of 5 patients with acute mass asphyxial gas poisoning with pulmonary vesicles who were admitted to the department of toxicology of this hospital in June 2019 and received nasal high-flow humidification and oxygen therapy. The oxygenation index, airway humidification and prognosis were observed.Results:All the 5 patients were successfully transferred to nasal catheter for oxygen inhalation after nasal high-flow humidification and orygen therapy without intubation. When discharged from the hospital without oxygen, pH: 7.36-7.42, PO 2:82-106 mmHg, PCO 2:32-39 mmHg. All the white blood cells and myocardial enzymes were normal, and there was no brain injury, perinasal skin damage and abdominal distension. Conclusion:Nasal high-flow humidification and oxygen therapy can effectively improve the efficacy of oxygen therapy for patients with acute mass asphyxial gas poisoning with pulmonary vacuoles.