噪声与高温联合作用致作业人群听力损失的Meta分析
Meta analysis of hearing loss caused by the combined effect of noise and heat in the working population
摘要目的:用Meta分析方法探讨噪声与高温联合作用对劳动者发生职业性听力损失的影响。方法:于2020年8月,检索中国知网、中国生物医学文献服务系统、万方数据知识服务平台、维普官方数据库、Medline及PubMed数据库2005年1月至2020年8月发表的关于接触噪声和高温与职业性听力损失关系的中文和英文文献,以噪声(noise)、高温(heat or hyperthermia)、听力(hearing)为关键词。利用Stata 12.0软件对所选定的数据进行分析,计算纳入文献的合并 OR(95% CI)值;利用敏感性分析探究异质性来源并分析发表偏倚。 结果:纳入分析的文献共14篇(中文14篇,英文0篇),纳入研究对象38 654人,其中噪声和高温联合作用组工人6 411人,单纯噪声组工人32 243人。噪声和高温联合作用组工人发生听力损失的概率是单纯噪声组工人的1.39倍(95% CI:1.14~1.69)。效应量 OR经敏感性分析结果稳定,纳入文献经Egger's和Begg's法检验不存在发表偏倚( Z=0.38, P=0.702; t=-0.74, P=0.476)。 结论:同时接触噪声和高温可能增加噪声作业场所劳动者听力损失的发生风险。
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abstractsObjective:To explore the effect of the combined effect of noise and heat on occupational hearing loss of workers by using Meta-analysis method.Methods:In August 2020, the Chinese and English literature on the relationship between exposure to noise and heat and occupational hearing loss published from January 2005 to August 2020 by CNKI, China Biomedical Literature Service System, Wanfang Data Knowledge Service Platform, VIP Official Database, Medline and PubMed Databases were searched, using noise, heat or hyperthermia, hearing as keywords. The selected data were analyzed by Stata 12.0 software, and the combined OR (95% CI) value included in the literature was calculated. Sensitivity analysis was used to explore the source of heterogeneity and analyze publication bias. Results:A total of 14 literatures (14 in Chinese, 0 in English) were included in the analysis, and 38654 subjects were included, including 6411 workers in the noise and heat combined effect group and 32243 workers in the noise alone group. The probability of hearing loss in the noise and heat combined effect group was 1.39 times higher than that in the noise alone group (95% CI: 1.14-1.69). The effect size OR was stable after sensitivity analysis, and there was no publication bias in the included literatures tested by Egger's and Begg's Method ( z=0.38, P=0.702, t=-0.74, P=0.476) . Conclusion:Simultaneous exposure to noise and heat may increase the risk of hearing loss for workers in noisy workplaces.
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