摘要目的:探讨电焊工尘肺患者疾病负担现状及其影响因素，为采取有针对性的干预措施提供科学依据。方法:于2022年6月至2023年6月，选取1956至2020年江苏省电焊工尘肺患者为研究对象（974例），采用伤残调整寿命年（DALY）等作为研究疾病负担的综合指标，计算患者因疾病所产生的直接和间接经济损失，利用多元线性回归法探讨影响疾病负担的因素。结果:江苏省报告的974例电焊工尘肺患者，累计损失的DALY为6 300.73人年，人均损失6.47人年，其中因伤残所损失的健康寿命年为6 156.50人年（97.71%），因早死所损失的健康寿命年为144.23人年（2.29%）。多元线性回归分析显示，影响DALY的主要因素为伤残等级、诊断年龄、尘肺期别和接尘工龄（ P<0.05）。974例电焊工尘肺患者所造成的总经济损失为1 831 838 160.18元，人均损失为1 880 737.33元；其中直接经济损失为970 917 563.75元（53.00%），间接经济损失为860 920 596.43元（47.00%）。 结论:电焊工尘肺给患者造成严重的疾病负担，同时给个人和社会造成了巨大的经济损失，严重阻碍了社会的发展，采取有效控制措施预防电焊工尘肺发病是减少其疾病负担的关键。

abstractsObjective:To investigate the current status of disease burden and its influencing factors among welder's pneumoconiosis patients, and provide scientific basis for taking targeted intervention measures.Methods:From June 2022 to June 2023, the patients with welder's pneumoconiosis in Jiangsu Province were selected from 1956 to 2020 as the research objects, and disability adjusted life years (DALY) were used as the comprehensive index to study the disease burden. The direct and indirect economic losses caused by the diseases were calculated, and the factors affecting the disease burden were discussed by multiple linear regression method.Results:A total of 974 cases of welder's pneumoconiosis were reported in Jiangsu Province, the cumulative loss of DALY was 6300.73 person-years, and the per capita loss was 6.47 person-years. Among them, the healthy life years lost due to disability (YLD) was 6156.50 person-years (97.71%) , and the healthy life years lost due to premature death (YLL) was 144.23 person-years (2.29%) . Multiple linear regression analysis showed that the main factors affecting DALY were disability grade, diagnostic age, pneumoconiosis grade and length of dust exposure ( P<0.05) . The total economic loss caused by 974 welder's pneumoconiosis patients was 1831838160.18 yuan, and the per capita loss was 1880737.33 yuan. Among them, the direct economic loss was 970917563.75 yuan (53.00%) , and the indirect economic loss was 860920596.43 yuan (47.00%) . Conclusion:Welder's pneumoconiosis causes serious disease burden to patients, and at the same time causes huge economic losses to individuals and society, which seriously hinders the development of society. Taking effective control measures to prevent the incidence of welder's pneumoconiosis is the key to reduce the disease burden.