摘要目的:应用起立-行走计时测试(Timed Up and Go Test，TUGT)探究社区老年人群运动功能与情绪、认知、睡眠方面的相关性。方法:横断面研究，2021年12月至2023年8月在中国北京市、天津市、浙江省、广东省、海南省随机招募60～90岁共739名受试者，根据TUGT时间(t)，将受试者分为运动正常组、运动轻度异常组和运动明显异常组。收集基本信息，并应用TUGT评估运动功能，中国修订的简易智力状态检查量表(Mini-mental State Examination，MMSE)评估认知功能，患者健康问卷抑郁量表(Patient health questionnaire-9，PHQ-9)评估抑郁程度，Epworth嗜睡量表(Epworth Sleepiness Scale，ESS)评估过度日间嗜睡程度。分析受试者运动功能与认知、情绪及睡眠的相关性。结果:收缩压、心率、PHQ-9、MMSE、ESS得分是TUGT时间的影响因素。TUGT时间与PHQ-9及ESS得分呈正相关，与收缩压、心率、MMSE得分呈负相关，与MMSE子成分中定向力、即刻记忆力及语言能力呈负相关，差异均具有统计学意义(均 P<0.05)。logistic回归分析显示：PHQ-9得分升高(运动轻度异常组 OR＝1.099，95% CI：1.045～1.155， P<0.001；运动明显异常组 OR＝1.150，95% CI：1.066～1.242， P<0.001)、MMSE得分降低(运动轻度异常组 OR＝0.939，95% CI：0.886～0.995， P<0.033；运动明显异常组 OR＝0.793，95% CI：0.729～0.862， P<0.001)、ESS得分升高(运动轻度异常组 OR＝1.139，95% CI：1.094～1.186， P<0.001；运动明显异常组 OR＝1.203，95% CI：1.132～1.279， P<0.001)与运动功能下降独立相关。 结论:抑郁状态、认知障碍及过度日间嗜睡与社区老年人群运动功能下降具有相关性，TUGT可用于社区老年人群的运动功能下降的早期筛查。

abstractsObjective:To apply the Timed Up and Go Test(TUGT)to investigate the correlation between motor function, emotional state, cognitive function, and sleep quality among elderly individuals in the Chinese community.Methods:A cross-sectional study was conducted, involving 739 subjects aged 60 to 90 years, who were randomly recruited from December 2021 to August 2023 across Beijing, Tianjin, Zhejiang, Guangdong, and Hainan Provinces in China.Basic demographic information was collected, and the TUGT was utilized to assess motor function.Based on the TUGT time(t), the subjects were divided into three groups: normal motor function group, mild motor abnormality group, and significant motor abnormality group.Cognitive function was evaluated using the Chinese Revised Mini-Mental State Examination(MMSE), while the Patient Health Questionnaire Depression Scale(PHQ-9)was employed to measure the degree of depression.Additionally, the Epworth Sleepiness Scale(ESS)was used to assess excessive daytime sleepiness.The correlation between subjects' motor function and their cognitive abilities, mood, and sleep was subsequently analyzed.Results:Systolic blood pressure, heart rate, PHQ-9, MMSE, and ESS scores were identified as significant factors influencing TUGT time.Specifically, TUGT time was positively correlated with PHQ-9 and ESS scores, while exhibiting negative correlations with systolic blood pressure, heart rate, and MMSE scores.Additionally, TUGT time was negatively correlated with the MMSE subcomponents of orientation, immediate memory, and verbal ability.All observed differences were statistically significant(all P<0.05).Logistic regression analysis indicated that an increase in the PHQ-9 score was associated with an odds ratio( OR)of 1.099(95% CI: 1.045-1.155, P<0.001)(mild motor abnormality group)and 1.150(95% CI: 1.066-1.242, P<0.001)(Significant motor abnormality group).Additionally, a reduction in the MMSE score was observed, with an OR of 0.939(95% CI: 0.886-0.995, P<0.001)(mild motor abnormality group)and 0.793(95% CI: 0.729-0.862, P<0.001)(Significant motor abnormality group).Furthermore, an increase in the ESS score was noted, with ORs of 1.139(95% CI: 1.094-1.186, P<0.001)(mild motor abnormality group)and 1.203(95% CI: 1.132-1.279, P<0.001)(Significant motor abnormality group).These findings suggest that these variables are independently related to decreased motor function. Conclusions:Depression, cognitive impairment, and excessive daytime sleepiness are independent risk factors for motor dysfunction among elderly individuals in community settings.The Timed Up and Go Test TUGT can be utilized for the early screening of motor function decline in this population.