摘要目的：了解广东省某经济欠发达地区中低档女性性工作者（FSW）感染HIV和性传播疾病（STD）的状况并分析其危险因素。方法横断面调查，通过绘制分布图，采用等比例等概率抽样方法，对抽中的中低档FSW进行调查，获取人口学特征、性行为、吸毒行为等信息，并抽取5 ml静脉血进行HIV、梅毒及单纯疱疹病毒2型（HSV-2）检测。结果该地区中低档FSWs的HIV感染率为0.3%（2/575）；STDs感染率为32.2%（185/575），其中梅毒感染率为4.9%（28/575），HSV-2感染率为30.6%（176/575）。多因素非条件logistic分析结果显示使用毒品（OR＝3.91，95%CI：1.17～13.03）为感染STDs的危险因素；接受过干预服务（OR＝0.14，95%CI：0.04～0.52）、教育程度高（OR＝0.40，95%CI：0.19-0.83）、中档（相对于低档）（OR＝0.27，95%CI：0.09～0.79）为感染STD的保护性因素。结论广东省某经济欠发达地区中低档FSW均存在不同程度HIV/STD感染及危险行为，低档FSW更为严重，需加强对该类人群的宣传干预，预防当地HIV/STD传播。

abstractsObjective To explore the prevalence of HIV,sexually transmitted diseases (STDs) and associated factors among medium/low level female sex workers (FSWs) in an under-developed city in Guangdong province. Methods FSWs were reached by probability proportionate to size sampling through mapping. A cross-sectional survey was conducted to investigate data on demographic characteristics,sexual behaviors,condom use and drug use. 5 ml blood samples were collected to test for human immunodeficiency virus(HIV),syphilis and HSV-2. Results The prevalence rates of HIV,syphilis and HSV-2 were 0.3%(2/575),4.9%(28/575) and 30.6%(176/575) respectively,and 32.2%(185/575) for STDs. Results from multivariate unconditional logistic regression model indicated that drug use (OR=3.91,95%CI:1.17-13.03) was the independent risk factor for STDs infection. Risks as ever accepted intervention program (OR=0.14,95%CI:0.04-0.52),with higher education level (OR=0.40,95%CI:0.19-0.83) and medium-fee charged FSWs(OR=0.27,95% CI:0.09-0.79) were protective factors for STDs. Conclusion Sources of STDs and related risk factors were comprehensive among medium/low FSWs,especially for the latter,whith all calling for multi-sector cooperation to explore the effective intervention program in this population.