摘要目的 研究尿道下裂合并先天性上睑下垂的发病情况和两者的关联性. 方法 调查254例尿道下裂患儿上睑下垂的发病率和程度,与普通人群上睑下垂发病率进行比较,分析不同类型尿道下裂与上睑下垂发病率和程度的相关性. 结果 本组尿道下裂患儿合并先天性上睑下垂的发病率为4.72％ (12/254),高于普通人群的0.12％,差异有统计学意义(P＜0.05).重度上睑下垂5例,中度5例,轻度2例.后段型尿道下裂上睑下垂的发病率为8.51％ (8/94),高于前、中段型的2.50％(4/160),差异有统计学意义(P＜0.05).后段型尿道下裂重度上睑下垂的发病率为2.13％,与前、中段型尿道下裂的1.88％相比差异无统计学意义(P＞0.05). 结论 先天性上睑下垂是尿道下裂生殖系统外的常见合并畸形.尿道下裂的程度与上睑下垂的发病率呈正相关,与上睑下垂的程度无明显相关.2种疾病可能有共同的致病或易感因素.

abstractsObjective To study the concurrence of congenital ptosis and hypospadias and the relationship between the two. Methods The incidence rate and degree of ptosis were recorded for 254 cases of hypospadias. Results The morbidity of ptosis in hypospadias cases was 4.72％.The posterior hypospadias group had a higher ptosis rate than the anterior and middle hypospadias groups,P ＜ 0.05. While there was no statistical difference of severe ptosis morbidity rates between these two groups. Conclusions Congenital ptosis is a common concurrent anomaly of hypospadias outside the urogenital system.The severity of hypospadias is relevant with the morbidity of ptosis but not with the degree of ptosis.Hypospadias and ptosis may share common pathogenic or susceptive factors.