摘要169 例短病程2型糖尿病患者,根据大动脉内中膜厚度(IMT)分为动脉粥样硬化(AS)组和非AS组,测定血清淀粉样蛋白A(SAA)水平,结果显示2型糖尿病组SAA水平较对照组高,AS组高于非AS组,并与年龄、体重指数、腰臀比及颈总动脉IMT呈正相关;年龄、C反应蛋白及SAA是影响颈总动脉IMT的相关因素.

abstractsA total of 169 patients with short-duration type 2 diabetic mellitus (DM) were divided into atherosclerosis (AS) group and non-AS group according to the intima-media thickness (IMT) of three conducting arteries.The level of serum amyloid A (SAA) was assayed by ELISA.The results showed that SAA level of type 2 DM patients increased significantly, patients in AS group showed higher SAA level than that in non-AS group, and SAA level was positively correlated with age, body mass index, waist hip ratio and IMT of common carotid artery.Age, C-reactive protein and SAA level are the major risk factors for IMT of common carotid artery.