摘要自身免疫性垂体炎是由自身免疫反应引起的垂体炎症性疾病,根据病因可分为原发性和继发性,临床表现为垂体肿大和垂体功能低下,诊断依靠临床症状和影像学表现,病理检查是诊断的金标准.治疗目标为缩小垂体肿块、激素替代及缓解高催乳素血症.本文对淋巴细胞性垂体炎、细胞毒T淋巴细胞相关抗原4抗体相关性垂体炎和IgG4相关性垂体炎的流行病学特点、发病机制及临床诊治进行综述.

abstractsAutoimmune hypophysitis is an inflammation of the pituitary gland resulting from autoimmune response, which can be classified as primary hypophysitis and secondary hypophysitis according to the etiology.The clinical presentation includes hypopituitarism and a pituitary mass.The diagnosis is based on clinical findings and radiology, while the pathology serves as the golden standard.The treatment is aimed at reducing the size of the pituitary mass, replacing the defective hormones and decreasing hyperprolactinemia.This review is about the epidemiology, pathogenesis, diagnosis, and treatment of lymphocytic hypophysitis, hypophysitis secondary to cytotoxic T-4 blockade, and IgG4-related hypophysitis.