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社区中老年人颈围与心血管危险因素的相关性分析

Relationships between the neck circumference and cardiovascular risk factors of middle-aged and elder people in community

摘要目的:了解社区中老年人颈围与心血管危险因素的相关性。方法对社区40岁及以上居民9665名进行问卷调查,检测身高、体重、颈围、腰围、血压、血脂、血糖、HbA1C、空腹胰岛素等。采用SPSS 16.0进行统计学分析。结果(1)无论男女,颈围与腰围、体重指数、血压、血糖、低密度脂蛋白胆固醇、三酰甘油和胰岛素抵抗指数均呈正相关、与高密度脂蛋白胆固醇呈负相关(均P<0.05);男性颈围与总胆固醇呈正相关(P<0.01),女性颈围与总胆固醇不相关(P>0.05)。(2)男性颈围增大会增加糖尿病的发生风险(OR=1.14,95%CI 1.02~1.28);女性颈围增大会增加高血压(OR=1.17,95%CI 1.08~1.27)、糖尿病(OR=1.24,95%CI 1.13~1.37)、血脂异常(OR=1.17,95% CI 1.09~1.27)和胰岛素抵抗(OR=1.15,95% CI 1.06~1.26)的发生风险。在女性颈围影响较男性更大。结论颈围是心血管危险因素独立关联的指标。

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abstractsObjective To investigate the relationships between the neck circumference and cardiovascular risk factors of middle-aged and elder people in a community. Methods Altogether 9 665 community residents ( age≥40 years) were enrolled in the present study. The height, weight, neck circumference, waist circumference, blood pressure, total cholesterol, triglycerides, low density lipoprotein-cholesterol ( LDL-C ) , high density lipoprotein-cholesterol ( HDL-C) , blood glucose, glycosylated hemoglobin, and fasting insulin were measured, and documented in the questionnaire along with other basic information. After adjusted for age, Pearson correlation coefficient was used to analyze the relationship between the neck circumference and the binary variables of cardiovascular risk factors. SPSS16.0softwarewasusedforstatisticalanalysis. Results (1)Theneckcircumferenceswere(37.11±2.79)cm in male and (32. 79 ± 2. 31) cm in female;which were higher in males than females. In both males and females, after adjusted for age, the neck circumference was positively correlated to waist circumference, body mass index, blood pressure, plasma glucose, LDL-C, triglycerides, and insulin resistance, the neck circumference was negatively correlated to HDL-C(all P<0. 05);The neck circumference of males was positively correlated to total cholesterol(P<0. 01);The neck circumference of females was not correlated with total cholesterol(P>0. 05). (2) After adjusted for body mass index and the waist circumference, the neck circumference of males increased with the risk of diabetes ( OR=1. 14, 95% CI 1. 02-1. 28);while the higher neck circumference of females increased the risk of hypertension (OR=1.17,95% CI1.08-1.27),diabetes(OR=1.24,95% CI1.13-1.37),dyslipidemia(OR=1.17,95%CI 1.09-1.27),andinsulinresistance(OR=1.15,95% CI1.06-1.26). Theneckcircumferenceexertedhigher impact on women than it did on men. Conclusion The neck circumference is associated with the cardiovascular risk factors. This association in females is stronger than that in males. The neck circumference seems to be an independent indicator for the cardiovascular risk.

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作者 霍亚南 [1] 徐芳华 [1] 徐艳 [1] 章玉玲 [1] REACTION研究组 [1] 学术成果认领
栏目名称 临床研究
DOI 10.3760/cma.j.issn.1000-6699.2016.03.007
发布时间 2016-05-17
基金项目
国家代谢性疾病临床医学研究中心 科技部重大新药创制项目
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中华内分泌代谢杂志

中华内分泌代谢杂志

2016年32卷3期

213-216页

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