换一批胎儿编程：母体肥胖引起代际肥胖的研究现状及逆转途径
Fetal programming: research status and reversal of intergenerational obesity caused by maternal obesity
摘要胎儿编程指胚胎和胎儿期间，许多器官结构及功能经历的编程。胚胎和胎儿期间任何刺激和损害均可引起器官发生适应性改变，母体肥胖则是重要影响因素之一。本文依据最近涉及孕产妇肥胖动物模型和人类的研究，着重从胎儿编程角度出发，对母体肥胖所致代际肥胖的机制以及逆转策略作一综述，以期逆转育龄妇女肥胖对后代肥胖的影响。
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abstractsFetal programming refers to as the process that organ structures and related functions undergo programming at the embryo and fetus phase. Any stimulus and injuries during embryo and fetal development can lead to changes in multiple fetal organs. Among them, maternal obesity is an important factor. This work reviews the data from recent animal models and human regarding the effects of maternal obesity on fetal programming, with a particular focus on the mechanisms and reversal strategies.
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DOI
10.3760/cma.j.cn311282-20210827-00555
发布时间
2026-01-27（万方平台首次上网日期，不代表论文的发表时间）
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