摘要目的 研究专病门诊对他汀类药物在卒中二级预防中使用的影响.方法 回顾性总结568例在卒中门诊登记的缺血性卒中患者的人口经济学、个人既往史、LDL-C水平及他汀类药物使用等信息.结果 306例专病门诊患者的他汀类药物使用率为51.3%,而262例普通门诊患者的他汀类药物使用率仅为7.6%.在专病门诊中,71.6%有血脂异常者和44.8%无血脂异常者使用他汀类药物,明显高于普通门诊者的27.1%和2.0%.专病门诊患者中LDL-C＞3.4 mmol/L者他汀类药物使用率显著高于低于此值者(25.6%比14.7%,P=0.017).结论 普通门诊中他汀类药物使用率极低,而专病门诊则能显著提高他汀类药物的使用率,缩小了临床实践与指南的差距.

abstractsObjective To describe the impact of stroke clinic on the usage of statins for secondary prevention of ischemic stroke.Methods Data about the demography, social economic status, personal histories, blood lipid profiles, and the status of the usage of statins from 568 serial ischemic stroke patients were retrospectively analysed.Results A total of 51.3% patients followed up in stroke clinic ( 306 patients) and 7.6% patients followed up in general clinic (262 patients) were treated with statins.71.6% patients with and 44.8% patients without hyperlipidemia in stroke clinics were taking statins, which were higher than that patients in the general clinics(27.1% and 2.0% respectively).The patients in the stroke clinics with high LDL-C level ( ＞ 3.4 mmol/L) were more likely to be treated with statins than those with lower level (25.6% vs 14.7%, P = 0.017).Conclusions The rate of statins usage is extremely low in stroke patients followed up in a general clinic, but it can been improved greatly in a stroke clinic.Stroke clinic can narrow the gap between the clinical practice and the guideline for secondary prevention of ischemic stroke.