摘要目的 探讨痤疮患者面部皮肤生理功能的特点,以期指导痤疮患者的治疗.方法 选取受试对象120例,试验组为痤疮患者60例,其中男20例,女40例,平均年龄23.4岁;对照组为健康志愿者60例,其中男20例,女40例,平均年龄25.1岁.运用无创性皮肤生理功能测试仪,测量受试者的面颊及T区(油脂分泌旺盛区域)皮肤油脂、面颊皮肤弹性和水分.结果 试验组而部T区油脂量为(199.98±58.21)μg/cm2,健康对照组为(117.55±63.16);μg/cm2,两组差异有统计学意义(t=7.34,P<0.05).试验组面颊油脂量为(154.45±55.06)μg/m2,健康对照组为(87.50±47.36)μg,cm2,两组差异有统计学意义(t=7.14,P<0.05).试验组皮肤弹性(0.7931±0.0755R)与健康对照组(0.7882±0.0498R)比较,差异无统计学意义(P>0.05),试验组皮肤水分(30.75%±3.87%)与健康对照组(30.94%±2.91%)比较,差异也无统计学意义(P>0.05).结论 痤疮患者颜面皮肤油脂分泌过多.

abstractsObjective To characterize the skin physiology function of patients with ache and to facilitate its treatment. Methods Sixty patients with acne (20 males and 40 females) and 60 healthy human controls (20 males and 40 females) were included into this study. The average age of patients and controls was 23.4 years and 25.1 years, respectively. Sebumeter was used to detect the sebum secretion in the following areas: forehead, nose, right and left cheeks, Cutometer(R) MPA580 to measure the skin elasticity, and Scalar Moisture Checker to test the skin hydration on right and left cheeks. Results A significant increase was observed in the level of sebum secretion in the T-zones (199.98±58.21 μg/cm2 vs 117.55±63.16 μg/cm2, t=7.34, P<0.05) as well as in the cheeks(154.45±55.06 μg/cm2 vs 87.50±47.36 μg/cm2, t=7.14, P< 0.05) in the patients compared with the controls. However, the level of skin elasticity and hydration was of no significant difference between the patients and controls (0.7931±0.0755R vs 0.7882±0.0498R, 30.75%±3.87% vs 30.94%±2.91%, respectively, both P>0.05). Conclusion Facial sebum secretion is increased in patients with acne.