摘要甲磺酸伊马替尼是治疗慢性髓性白血病和恶性胃肠道间质肿瘤的一线用药,其皮肤黏膜不良反应的发生率较高。作者通过复习国内外文献描述该药导致的各种皮肤黏膜症状,并总结其发病机制和治疗对策,旨在帮助皮肤科医生提高对该药皮肤黏膜不良反应的认识,给予及时诊治。
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abstractsImatinib mesylate is the first-line drug for the treatment of chronic myeloid leukemia and malignant gastrointestinal stromal tumors, and causes mucocutaneous adverse reactions at a high frequency. Based on Chinese and international literature, the authors comprehensively describe various mucocutaneous symptoms induced by imatinib mesylate, and summarize their pathogenesis and management strategies, aiming to help dermatologists improve their understanding of mucocutaneous adverse reactions to this drug, and provide timely diagnosis and treatment.
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