换一批长链非编码RNA在皮肤鳞状细胞癌中的作用机制进展
Mechanism of action of long non-coding RNAs in cutaneous squamous cell carcinoma
摘要长链非编码RNA（lncRNA）主要通过表观遗传修饰、mRNA选择性剪接调控、结合微小RNA等机制参与皮肤鳞状细胞癌（cSCC）的发生发展。本文综述近年来lncRNA在cSCC中调控的研究，探讨其作用机制，寻找cSCC潜在治疗靶点及生物标志物。
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abstractsLong non-coding RNAs (lncRNAs) participate in the occurrence and development of cutaneous squamous cell carcinoma (cSCC) mainly through epigenetic modification, mRNA alternative splicing, and binding to microRNAs. This review focuses on recent research progress in regulatory role of lncRNAs in cSCC, and discusses their mechanisms of action, aiming to seek potential therapeutic targets and biomarkers for cSCC.
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关键词
肿瘤，鳞状细胞RNA，未翻译表观基因组学选择性剪接长链非编码RNA发病机制皮肤鳞状细胞癌Neoplasms, squamous cellRNA, untranslatedEpigenomicsAlternative splicingLong non-coding RNAPathogenesisCutaneous squamous cell carcinoma
栏目名称
DOI
10.35541/cjd.20210099
发布时间
2023-10-15（万方平台首次上网日期，不代表论文的发表时间）
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